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Growing collaborations between organisations and increased NGS data sharing between locations has created a need for a more robust and secure data storage, analysis, access and integration system while ensuring high quality of the NGS data being produced. At the NGS Data Analysis and Informatics Conference' to be held on 10 - 11 December 2015 in Orlando, Florida - USA we will be discussing strategies to accurately analyse and scale-up informatics for the data generated through the NGS technology while ensuring quality & scalability of the data.